CART-T
Safety for Sensitive Samples

In addition to “traditional” sample storage in biobanks, there are other areas of application that also involve sample storage—specifically, the storage of highly sensitive samples in a regulated environment. CAR-T cell therapy is one such area, with its own unique requirements. For CAR-T therapies, in addition to traditional sample tubes, bags (often called blood bags or cryo-bags) are frequently used in cassettes (often referred to as blood cassettes or cryo-cassettes). These sample formats contain human samples that are frozen under controlled conditions, stored securely, transferred, and later administered to patients. This requires that the samples be stored and handled in a contamination-free and traceable manner. The HS200 S/M/L sample storage systems make this possible. Thanks to contamination-free gas-phase storage combined with automated sample handling at -130°C, contamination-free, automated, and mix-up-proof sample storage is ensured. In addition, the aWB offers the ideal solution for automatically freezing samples in a controlled and reproducible manner. Special temperature sensors enable the detection of the sample temperature without contaminating the sample. In combination with the available automated sample transfer systems at -130°C —either a rail system or self-driving robots—a fully automated CAR-T sample processing line can be implemented, right down to a one-click operation.

If you’d like to learn more, we look forward to hearing from you.